The Crescent City Connection in New Orleans, the most downstream bridge.
The Hernando de Soto Bridge in Memphis.
The I-35W Saint Anthony Falls Bridge in Minneapolis.
- 800zipcodes.com: offers a full list of U.S. cities starting with E.
This list proceeds upstream from the mouth to Minneapolis.
| Bridge | Length | main span | Type | lanes | Opening |
| Crescent City Connection | 4,093 m | 480 m | cantilever truss bridge | 2×4 | 1958 / 1988 |
| Huey P. Long Bridge | 2,462 m | 241 m | cantilever truss bridge | 2×3 | 1935 |
| Luling Bridge | 3,261 m | 372 m | cable-stayed bridge | 2×2 | 1983 |
| Gramercy Bridge | 945 m | 445 m | cantilever truss bridge | 2×2 | 1995 |
| Sunshine Bridge | 2,510 m | 251 m | cantilever truss bridge | 2×2 | 1964 |
| Horace Wilkinson Bridge | 4,313 m | 376 m | cantilever truss bridge | 2×3 | 1968 |
| Huey P. Long Bridge (Baton Rouge) | 1,792 m | 228 m | cantilever truss bridge | 2×2 | 1940 |
| John James Audubon Bridge | 3,927 m | 482 m | cable-stayed bridge | 2×2 | 2011 |
| Natchez–Vidalia Bridge | 1,282 m | 258 m | cantilever truss bridge | 2×2 | 1940 / 1988 |
| Vicksburg Bridge | 3,954 m | 265 m | cantilever truss bridge | 2×2 | 1973 |
| Greenville Bridge | 4,133 m | 420 m | cable-stayed bridge | 2×2 | 2010 |
| I-69 Mississippi River Bridge | ? m | ? m | TBD | 2×2 | ? |
| Helena Bridge | 1,586 m | 245 m | cantilever truss bridge | 1×2 | 1961 |
| Memphis & Arkansas Bridge | 1,592 m | 235 m | cantilever truss bridge | 2×2 | 1949 |
| Hernando de Soto Bridge | 5,954 m | 274 m | arch bridge | 2×3 | 1973 |
| Caruthersville Bridge | 2.165 m | 280 m | cantilever truss bridge | 2×2 | 1976 |
| Cairo Mississippi River Bridge | 1,577 m | 214 m | cantilever truss bridge | 1×2 | 1929 |
| Cairo I-57 Bridge | 1.246 | 250 m | arch bridge | 2×2 | 1978 |
| Bill Emerson Memorial Bridge | 1,205 m | 350 m | cable-stayed bridge | 2×2 | 2003 |
| Chester Bridge | 861 m | 204 m | truss bridge | 1×2 | 1942 |
| Jefferson Barracks Bridge | 1,219 m | 277 m | arch bridge | 2×3 | 1983 / 1992 |
| Poplar Street Bridge | 660 m | 183 m | girder bridge | 2×4 | 1967 |
| Eads Bridge | 1,964 m | 158 m | arch bridge | 2×2 | 1874 |
| Martin Luther King Bridge (St. Louis) | 1,222 m | 293 m | cantilever truss bridge | 1×3 | 1951 |
| Stan Musial Veterans Memorial Bridge | 854 m | 457 m | cable-stayed bridge | 2×3 | 2014 |
| McKinley Bridge | 1,924 m | 158 m | truss bridge | 1×2 | 1910 |
| New Chain of Rocks Bridge | 1,649 m | 74 m | girder bridge | 2×2 | 1966 |
| Clark Bridge | 1,408 m | 230 m | cable-stayed bridge | 2×2 | 1994 |
| Champ Clark Bridge | 697 m | 127 m | girder bridge | 1×2 | 1928 / 2019 |
| Mark Twain Memorial Bridge | 1,369 m | 195 m | truss bridge | 2×2 | 2000 |
| Quincy Memorial Bridge | 1,070 m | 191 m | truss bridge | 1×2 | 1928 |
| Bayview Bridge | 1,374 m | 274 m | cable-stayed bridge | 1×2 | 1987 |
| Keokuk–Hamilton Bridge | 1,018 m | 90 m | girder bridge | 2×2 | 1985 |
| Fort Madison Bridge | 1,091 m | 160 m | swing bridge | 1×2 | 1927 |
| Great River Bridge | 691 m | 201 m | cable-stayed bridge | 2×2 | 1993 |
| Norbert F. Beckey Bridge | 920 m | 156 m | truss bridge | 1×2 | 1972 |
| Sergeant John F. Baker, Jr. Bridge | 1,278 m | 175 m | arch bridge | 2×2 | 1973 |
| Rock Island Centennial Bridge | 1,355 m | 166 m | arch bridge | 2×2 | 1940 |
| Government Bridge | 490 m | 111 m | swing bridge | 1×2 | 1896 |
| I-74 Bridge | 1,036 m | 242 m | arch bridge | 2×4 | 1935 / 1959 / 2020 |
| Fred Schwengel Memorial Bridge | 1,062 m | 113 m | girder bridge | 2×2 | 1966 |
| Gateway Bridge (Illinois–Iowa) | 1,270 m | 197 m | suspension bridge | 1×2 | 1956 |
| Mark N. Norris Bridge | 917 m | 152 m | cantilever truss bridge | 1×2 | 1975 |
| Savanna–Sabula Bridge | 750 m | 166 m | arch bridge | 1×2 | 1932 / 2017 |
| Julien Dubuque Bridge | 1,756 m | 258 m | arch bridge | 1×2 | 1943 |
| Dubuque–Wisconsin Bridge | 899 m | 204 m | arch bridge | 2×2 | 1982 |
| Marquette–Joliet Bridge | 781 m | 141 m | arch bridge | 1×2 | 1975 |
| Black Hawk Bridge | 504 m | 200 m | cantilever bridge | 1×2 | 1931 |
| Mississippi River Bridge (La Crosse, Wisconsin) | 784 m | 145 m | truss bridge + arch bridge | 2×2 | 1940 / 2004 |
| I-90 Mississippi River Bridge | 759 m | 137 m | girder bridge | 2×2 | 1967 |
| Main Channel Bridge (Winona) | 679 m | 139 m | cantilever truss bridge | 1×2 | 1942 |
| Wabasha–Nelson Bridge | 750 m | 143 m | truss bridge | 1×2 | 1988 |
| Red Wing Bridge | 501 m | 132 m | cantilever truss bridge | 1×2 | 1960 / 2019 |
| Hastings Bridge | 166 m | arch bridge | 2×2 | 2013 | |
| Wakota Bridge | 576 m | 142 m | cantilever bridge | 2×5 | 2006 / 2010 |
| Lafayette Bridge | 1,029 m | 110 m | girder bridge | 2×2 | 1968 |
| Robert Street Bridge | 468 m | 81 m | arch bridge | 2+3 | 1926 |
| Wabasha Street Bridge | 381 m | 121 m | cantilever bridge | 2×2 | 1998 |
| High Bridge (St. Paul) | 841 m | 158 m | arch bridge | 1×2 | 1987 |
| Lexington Bridge (Mississippi River) | 429 m | girder bridge | 2×3 | 2004 | |
| Fort Road Bridge | 365 m | 91 m | girder bridge | 2×2 | 1961 |
| Intercity Bridge | 465 m | 100 m | arch bridge | 2×2 | 1927 |
| Lake Street-Marshall Bridge | 452 m | 169 m | arch bridge | 1×4 | 1992 |
| Franklin Avenue Bridge | 322 m | 122 m | arch bridge | 1×2 | 1923 |
| Dartmouth Bridge | 305 m | 104 m | girder bridge | 2×5 | 1964 |
| I-35W Saint Anthony Falls Bridge | 371 m | 154 m | cantilever bridge | 2×5 | 2008 |
